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Cheapest USA flight offers from £405

72-hour sale: ends 9am Tuesday

Been dreaming of a holiday in San Diego, or just a short break in Chicago? Discover America this year with Opodo. We've got our cheapest daily flight offers to the top US destinations.

The great outdoors

Departs
Destination
Departs
Returns
Fly from
01 Jan 70
01 Jan 70
01 Jan 70
01 Jan 70
01 Jan 70
01 Jan 70
01 Jan 70
01 Jan 70
01 Jan 70
01 Jan 70

Bright lights, big city

Departs
Destination
Departs
Returns
Fly from
London
Boston
08 Jun 16
15 Jun 16
London
New York
15 Jun 16
22 Jun 16
01 Jan 70
01 Jan 70
London
Chicago
04 May 16
11 May 16
London
Detroit
25 May 16
01 Jun 16
London
Seattle
22 Jun 16
29 Jun 16
London
Las Vegas
18 May 16
25 May 16
01 Jan 70
01 Jan 70
London
Washington
04 May 16
11 May 16
London
Atlanta
11 May 16
18 May 16

Florida fun

Departs
Destination
Departs
Returns
Fly from
London
Miami
11 May 16
18 May 16
London
Orlando
04 May 16
11 May 16
London
Tampa
23 Oct 14
27 Oct 14
01 Jan 70
01 Jan 70

Broaden your horizons

Departs
Destination
Departs
Returns
Fly from
01 Jan 70
01 Jan 70
01 Jan 70
01 Jan 70

The sound of the States

Departs
Destination
Departs
Returns
Fly from
London
Houston
04 May 16
11 May 16

California dreamin'

Departs
Destination
Departs
Returns
Fly from
London
Los Angeles
25 May 16
01 Jun 16
London
San Diego
18 May 16
25 May 16
London
San Francisco
11 May 16
18 May 16
Terms and conditions:Please note that all offers are subject to availability. Places are limited and can't be guaranteed. Flight offers may contain blackout periods within the listed date range. Weekend supplements may apply for travel on Friday, Saturday and Sunday. Taxes and charges are outside of Opodo's control and may vary day-to-day, and according to routing. The correct taxes and charges will be calculated and displayed before you confirm your purchase.