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Cheapest USA flight offers from £401

72-hour sale: ends 9am Tuesday

Been dreaming of a holiday in San Diego, or just a short break in Chicago? Discover America this year with Opodo. We've got our cheapest daily flight offers to the top US destinations.

The great outdoors

Departs
Destination
Departs
Returns
Fly from
London
Denver
01 May 15
08 May 15
London
Phoenix
15 May 15
23 May 15
London
Charlotte
23 May 15
30 May 15
London
Cleveland
09 Jun 15
16 Jun 15
London
Minneapolis
26 May 15
30 May 15

Bright lights, big city

Departs
Destination
Departs
Returns
Fly from
London
Boston
26 May 15
02 Jun 15
London
New York
28 May 15
15 Jun 15
London
Philadelphia
11 May 15
28 May 15
London
Chicago
20 May 15
26 May 15
London
Detroit
01 Jun 15
16 Jun 15
London
Seattle
30 Apr 15
07 May 15
London
Las Vegas
02 May 15
04 May 15
London
Dallas
08 May 15
18 May 15
London
Washington
27 May 15
03 Jun 15
Manchester
Atlanta
14 May 15
19 May 15

Florida fun

Departs
Destination
Departs
Returns
Fly from
London
Miami
20 May 15
27 May 15
London
Orlando
25 Apr 15
09 May 15
London
Tampa
23 Oct 14
27 Oct 14
London
Fort Lauderdale
18 May 15
01 Jun 15

Broaden your horizons

Departs
Destination
Departs
Returns
Fly from
London
Cincinnati
29 Apr 15
06 May 15
London
Raleigh
08 May 15
13 May 15

The sound of the States

Departs
Destination
Departs
Returns
Fly from
London
Houston
28 Apr 15
05 May 15

California dreamin'

Departs
Destination
Departs
Returns
Fly from
London
Los Angeles
06 May 15
13 May 15
London
San Diego
03 May 15
10 May 15
London
San Francisco
06 May 15
13 May 15
Terms and conditions:Please note that all offers are subject to availability. Places are limited and can't be guaranteed. Flight offers may contain blackout periods within the listed date range. Weekend supplements may apply for travel on Friday, Saturday and Sunday. Taxes and charges are outside of Opodo's control and may vary day-to-day, and according to routing. The correct taxes and charges will be calculated and displayed before you confirm your purchase.